2, 4, 5 The literature search for this report did not find epidemiological data for lipedema in Canada. 2 However, lipedema is believed to affect nearly 11% of adult women, 3 with noted significant differences in prevalence worldwide. 1, 2 Lipedema does not yet have a registered diagnosis in the International Classification of Diseases (ICD-10) of the World Health Organization (WHO), making it difficult to establish its prevalence. 1, 2 The condition is relatively rare and often seen in patients with a family history of the disease. 1 It occurs almost exclusively in females, although a few cases in men have been reported. It is important to talk to your doctor before you start taking high doses of any vitamin, including vitamin B12.Lipedema is a disorder characterized by large amount of subcutaneous fat in the upper and lower legs due to both hyperplasia and hypertrophy. It is important for you to get prompt medical care if your symptoms are severe or are progressively getting worse. You should stop taking vitamin B12 immediately if you experience any side effects of too much B12. If you experience anaphylaxis, you or someone else should call 911.ĭo not take vitamin B12 supplements if you are allergic to vitamin B12, cobalt, or any other ingredients this supplement contains. It also makes it hard for you to breathe and swallow. Anaphylaxis causes your face, tongue, and throat to become swollen. Vitamin B12 can also cause a very rare but potentially life-threatening allergic reaction called anaphylaxis. A rare and slow-growing cancer of the blood known as polycythemia vera is also possible. Vitamin B12 injections can also cause vein thrombosis, which increases your risk of developing blood clots. Early on in treatment, these injections can cause pulmonary embolism (a blood clot that travels to one of your lungs from somewhere else in your body and blocks blood flow in the affected lung) and congestive heart failure. Other side effects of vitamin B12 injections are more serious. Therefore, taking high doses is not necessary or beneficial if you do not have an increased need for vitamin B12. How much vitamin B12 does your body absorb? How much does it need? For example, only about 10-mcg of a 500-mcg dose is actually absorbed by your body if you do not have vitamin B12 deficiency. It is unlikely for high doses to harm most people, but you should not take excessively high doses if it is not recommended by your doctor first. Studies have found that taking up to 2 milligrams (equivalent to 2,000 mcg) of oral vitamin B12 supplements is safe and effective if you have vitamin B12 deficiency.Īlthough doses up to 2,000 mcg can be used safely to treat vitamin B12 deficiency, you should not take such a high dose if you do not have a deficiency. It is recommended that women who are breastfeeding take 2.8 mcg every day. The recommended daily intake (RDI) of vitamin B12 is 2.4 micrograms (mcg) for both women and men, but women who are pregnant or breastfeeding need more vitamin B12. Unborn babies have a higher risk of autism spectrum disorder if their mother has excessively high levels of vitamin B12 from supplementation. The participants in this particular study took a dose of 1 milligram (mg) of oral vitamin B12 supplements each day. The people who took the high doses of vitamin B12 were more at risk for heart attack, stroke, and death than the participants who took a placebo, but more research is needed to support this claim. For example, a study from 2010 found that participants who have diabetic neuropathy (decreased kidney function caused by diabetes) had a quicker decline in the functioning of their kidneys when they took high-dose supplements of vitamin B12.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |